Lymphocytic Colitis

Lymphocytic Colitis






Lymphocytic colitis is a disorder that causes swelling of large intestine. It is also known as microscopic colitis since this problem has to be examined under a microscope for diagnosing it. Two major types of colitis are recognized. One is collagenous colitis which is marked by thick protein layer on the tissue of the colon and the second is lymphocytic colitis which is marked by swelling or inflammation of colon tissue due to accumulation of white blood cells.

Symptoms :

The below symptoms are not the same for every person who has developed lymphocytic colitis. Nausea, incontinence of stool, passing loose stools, sudden Weight Loss and pain in the abdomen are some of the signs of this disorder.

Causes :

The causative factors are not specific and experts believe that this disorder can be caused due to certain factors like prolonged intake of certain medicines (that would destroy the soft lining of the colon), virus or bacterial infection (that may produce toxins destroying the inner lining) and autoimmune disorders like lupus or arthritis in which the body’s immune system will destroy healthy cells of the colon by mistake.

Who are at risk?

People who are aged, and have problems in their immune system are more prone to get disorders in colon than others. Women are likely to get more problem than men in their menopause age. Intake of certain medications like proton pump inhibitors, zantac and serotonin reuptake inhibitors can cause the risk of developing lymphocytic colitis.

Tests :

Your doctor will assess the symptoms given above and complete physical examination of your body. He would rule out the possibilities of Celiac Disease for Diarrhea and collect medical history from you. He may order for blood culture, biopsy of the tissue from your digestive tract (to rule out celiac disease), and Colonoscopy test for detecting intestinal disorders. Some doctors use sigmoidoscopy in which thin tubing fitted with camera is sent into the colon for viewing the position.

Treatment :

Mild forms of lymphocytic colitis do not require any treatment. You can visit the doctor if you have serious symptoms for more than a week. Your doctor will change your diet for arresting diarrhea problem. He would ask you to be on low fat and low fiber diet for some days till loose stool is controlled. He would prescribe medicines for managing diarrhea and further give anti-inflammatory medications that contain steroid or salicylates for reducing inflammation of the colon.

In case of immune related cause, then you will be given drugs for suppressing the immune system. If your body does not respond to any medicines and the symptoms are getting worse, he may suggest surgery for removing colon. This is done in rare cases.

Home Remedies :

For controlling diarrhea you can eat soft low fat diets. Avoid taking foods like beans, cauliflower and nuts that contains high fiber during this time. Replace them by rice and bananas. Eat small amounts of food frequently to help easy digestion. Drink plenty of water and fluids that contain sodium and potassium. Avoid coffee, tea and soft drinks which may worsen the symptoms. Restrict eating spicy foods that would aggravate diarrhea.

Lymphocytic Colitis – Symptoms, Causes, Treatment, Diet

Lymphocytic Colitis – Symptoms, Causes, Treatment, Diet

What is Lymphocytic Colitis?

Lymphocytic colitis is the inflammation of the colon that causes persistent non-bloody Diarrhea. This is considered a rare condition that seems to provide us a normal Colonoscopy result, but shall only reveal its presentation with a mucosal biopsy. Lymphocytic colitis is interconnected with collagenous colitis, a condition that has the same features as with lymphocytic colitis. Both are subtypes of the microscopic colitis, as these conditions are identified or diagnosed by taking a tissue sample for a microscope analysis. The condition is said not to be decisively known, for again its rarity. It has been noted that about 10% of those who suffer chronic diarrhea are believed to be suffering from this lymphocytic colitis. According to epidemiological report, lymphocytic colitis commonly affects those people aging from 60 to 80 years. But rare cases place the young, such as the children, to be affected with this condition. As reported, women are more affected than men.

The condition can be diagnosed through these tests:

Stool examination – The exam is only aimed to rule out infection, which may be a possible cause of diarrhea.

Colonoscopy or sigmoidoscopy – This shall view the insides of the colon of the client. Usually, the colon of those affected with microscopic colitis is normal. During these procedures, a sample may be extracted and shall be sent to the lab in order to indentify the causative agent or probable cause.

Lymphocytic Colitis Symptoms

As already mentioned, this disease process involves inflammation of the colon thus resulting to bowel irritation. This can be discomforting for the part of the affected and can be energy-wasting at the same time. Presently, here are the manifestations of lymphocytic colitis include the following:

• Non-bloody, chronic, watery diarrhea that can possibly cause for dehydration


• Abdominal cramps and bloating


• Sudden Weight Loss


• Nausea and vomiting


• Fecal incontinence

Causes of Lymphocytic Colitis

Lymphocytic colitis is caused by the mere inflammation of the colon, but the etiology of the condition is yet being understood. Primarily, it is caused by the increased levels of the lymphocytes or white blood cell in the colon. Others believed, according to theories, that a bacterial agent has triggered the disease process – for toxins can irritate the lining of a person’s colon. A viral agent is also identified as precipitating factor for lymphocytic colitis those who are immunocompromised are somehow greatly affected for their defenses are weaker and that place them susceptible to infections or inflammations.

Those at risk for this condition are the people who take medications such as the Clozaril, Comtan, Nexium and Prevacid. NSAIDS also place a person at risk for microscopic colitis. The elderly are also noted to be at risk for developing lymphocytic colitis.

Lymphocytic Colitis Treatment

The aim for the treatment course of lymphocytic colitis is to relieve the discomfort of the affected. Here are some of the medical remedies for the condition:

Surgical removal of the colon

Partial removal of the affected colon may be necessary in severe cases. This will only be recommended by the doctor when he or she assesses that the condition has gone to its worst.

Anti-diarrheal drugs

This shall control diarrhea and avoid dehydration. Loperamide (the first line drug) is usually prescribed along with bismuth subsalicylate (second line) and Lomotil.

Antispasmodics

This can relive the abdominal cramping complained by the client. Hyoscyamine is an agent usually prescribed by doctors.

Cholestyramine

Cholestyramine is a generic drug that would assist in the treatment process of lymphocytic colitis by absorbing some bile acids that can cause for further diarrhea.

Corticosteroids
These can help in reducing the inflammation and help control the discomfort of the affected. Prednisone and budesonide are prescribed by the doctor more frequently.

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Topical anti-inflammatory drugs

This can reduce the inflammation process. The topical form is much more recommended than the oral form, because of its possibility to result for gastric upset.

Immunosuppressants

These can reduce the activity of inflammation and relax the colon inflammation. These drugs would include methotrexate and azathioprine.

Lymphocytic Colitis Diet

The patients’ recommended diet should be complied properly in order to attain a good result. Once he or she is diagnosed with colitis, there is a need to follow this strict diet regimen:

Low fat, low fiber diet

This is to avoid gastric irritation and stimulate for more diarrheal episodes. It is known that fat and increased fiber diet can stimulate bowel movement.

Avoid taking NSAIDs

This is because of its effect to the colon and its contribution to the development of colitis.

Increase oral fluid intake

As a person is at risk for dehydration (constant or chronic diarrhea’s complication), he or she should replace the fluid losses. Providing the client with ORS every after a loose-bowel episode is in action.

Eat easy-to-digest foods

These foods are recommended as we need to avoid the stimulation of the gastric system. What happens with hard-to-digest foods is that there shall be more effort exerted by the gastric system, making it a difficult situation and causing another problem. As low-fiber diet is not recommended at first, we need to wean the client slowly so that no abrupt change can harm the colon.

Avoid irritating foods and avoid lactose-rich diet

These foods include the spicy, fatty and fried foods. These can only stimulate irritation and for more diarrheal episodes. Milk can place a patient to more episodes of diarrhea most especially if he or she is lactose-intolerant.